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Yimon Aye

Yimon Aye (Burmese: ရည်မွန်အေး; born 12 July 1980[1] in Burma) is an American chemist and molecular biologist. Currently she is a professor of chemistry & chemical biology at University of Oxford.[2]

Career

Aye spent her early life in Burma. She completed her undergraduate studies in chemistry at the University of Oxford and obtained her master's degree in 2004.[3] She joined Harvard University to study synthetic organic chemistry with David A. Evans, achieving her PhD in 2009.[4] She then moved to Massachusetts Institute of Technology as a Damon Runyon Cancer Research Foundation fellow to work with JoAnne Stubbe. There she performed research into the regulatory mechanisms of ribonucleotide reductase.[5]

In 2012, she started as an assistant professor at Cornell University, where she began her work on redox-dependent cell signaling and genome maintenance pathways. During this time, she developed REX technologies, new methods to facilitate the study of unconventional electrophile-regulated stress signaling paradigms.[6][7] REX technologies were one of the first approaches to forge direct links between upstream protein alteration by a reactive molecule and downstream responses.[4] From August 2018 to August 2024 she was an associate professor of chemistry at EPFL.[8]

Since September 2024 she's leading the Aye Lab at University of Oxford.[2]

Awards

Aye was awarded the NSF CAREER award and Beckman Young Investigator award in 2014,[9][10] the 2020 Eli Lilly Award in Biological Chemistry,[11] the 2022 Tetrahedron Young Investigator Award,[12] and the Klaus Grohe Prize 2024.[13]

Personal life

Yimon Aye's father Soe Thein is a former Commander-in-Chief of the Myanmar Navy.[14] She has a brother and a sister.[1]

References

  1. ^ a b "Council Decision 2012/98/CFSP of 17 February 2012 amending Decision 2010/232/CFSP renewing restrictive measures against Burma/Myanmar". Official Journal of the European Union. Retrieved 2022-08-05.
  2. ^ a b "Yimon Aye". Department of Chemistry, University of Oxford. Retrieved 2024-10-10.
  3. ^ admin (2018-01-12). "Interview with Dr.Yimon Aye Assistant Professor of Cornell University". Myanmar Insider. Retrieved 2020-09-21.
  4. ^ a b "2017 WCC Rising Star Dr. Yimon Aye – Corn... | ACS Network". communities.acs.org. Retrieved 2020-09-21.
  5. ^ "JoAnne Stubbe Research Group - MIT". web.mit.edu. Retrieved 2020-09-21.
  6. ^ Poganik, Jesse R.; Long, Marcus J. C.; Aye, Yimon (2019-02-11). "Interrogating Precision Electrophile Signaling". Trends in Biochemical Sciences. 44 (4): 380–381. doi:10.1016/j.tibs.2019.01.006. ISSN 0968-0004. PMC 6462755. PMID 30765181.
  7. ^ Long, Marcus J.C.; Urul, Daniel A.; Aye, Yimon (2020), "REX technologies for profiling and decoding the electrophile signaling axes mediated by Rosetta Stone proteins", Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part C, Methods in Enzymology, vol. 633, Elsevier, pp. 203–230, doi:10.1016/bs.mie.2019.02.039, ISBN 978-0-12-819128-6, PMC 7027669, PMID 32046846
  8. ^ "15 new professors appointed at the two Federal Institutes of Technology". www.admin.ch. Retrieved 2022-02-11.
  9. ^ "NSF Award Search: Award # 1351400 - CAREER: A Chemical Technology to Define Target-Specific Bioreactivity: Integrating Research and Education at the Crossroads of Chemistry and Biology". www.nsf.gov. Retrieved 2025-03-17.
  10. ^ "Yimon Aye is a Beckman Young Investigator | Cornell Chronicle". news.cornell.edu. Retrieved 2025-03-17.
  11. ^ Papageorgiou, Nik. "Yimon Aye wins 2020 Eli Lilly Award". News EPFL. Retrieved 2024-03-17.
  12. ^ Papageorgiou, Nik. "Yimon Aye wins Tetrahedron Young Investigator Award". News EPFL. Retrieved 2025-03-17.
  13. ^ Goedecke, Catharina (2024-09-01). "Klaus Grohe Prize 2024 for Yimon Aye". ChemistryViews. Retrieved 2025-03-17.
  14. ^ "ပြည်ခိုင်ဖြိုးကိုယ်စားလှယ်လောင်း ဝန်ကြီးဟောင်းများပိုင်ဆိုင်သည့် ကုမ္ပဏီများ". Myanmar NOW (in Burmese). 23 September 2020. Retrieved 2022-02-17.