List of highways numbered 250

Route 250, or Highway 250, may refer to:

• Manitoba Provincial Road 250
• Prince Edward Island Route 250

• National Route 250

• Japan National Route 250

• A250 road
• B250 road

• U.S. Route 250
• Arkansas Highway 250
• California State Route 250
• Georgia State Route 250 (former)
• Hawaii Route 250
• Illinois Route 250
• Indiana State Road 250
• Kentucky Route 250
• Minnesota State Highway 250
• Montana Secondary Highway 250
• Nebraska Highway 250
• New Mexico State Road 250
• New York State Route 250
• Oregon Route 250
• Pennsylvania Route 250 (former)
• Tennessee State Route 250
• Texas State Highway 250 (former)
• Texas State Highway Loop 250
• Farm to Market Road 250 (Texas)
• Utah State Route 250 (former)

Territories:

• Puerto Rico Highway 250