Esproquin

Esproquin is an α2-adrenergic receptor agonist derived from tetrahydroisoquinoline.[1] It has a positive inotropic effect, suggesting potential use in treatment of chronic heart failure.[2]

References

  1. ^ Gray AP, Shiley RH (July 1973). "Preparation and cardiovascular actions of a group of tetrahydroisoquinoline derivatives". Journal of Medicinal Chemistry. 16 (7): 859–61. doi:10.1021/jm00265a028. PMID 4146907.
  2. ^ Kotelanski B, Grozmann RJ, Cohn JN (1973). "Positive inotropic effect of oral esproquin in normal subjects". Clinical Pharmacology and Therapeutics. 14 (3): 427–33. doi:10.1002/cpt1973143427. PMID 4698571. S2CID 46266823.